“Innovating Health” Outstanding Young Speaker Webinar – Dr Shao Huilin
The growing emphasis on personalised medicine significantly increases the need to analyse key molecular markers. Compared to tissue biopsies, circulating biomarkers (liquid biopsies) can be conveniently and repeatedly obtained from biofluids with minimal complications. Extracellular vesicles have recently emerged as a promising circulating biomarker. Extracellular vesicles are nanometer-sized membrane vesicles actively shed off by cells and possess unique advantages, i.e., they abound in biofluids and harbour diverse molecular contents. This talk will describe various nanosensor systems that have been developed for quantitative analyses of diverse circulating biomarkers. These technologies integrate advances in device engineering, nanomaterial sciences and molecular biology. By enabling rapid, sensitive and cost-effective detection of circulating biomarkers, these platforms could significantly expand preclinical and clinical research’s reach in informing therapy selection, rationally directing trials, and improving sequential monitoring to achieve better clinical outcomes.
Dr Huilin Shao received her BA from Cornell University, with a double major in Biological Sciences and in Physics. She completed her dual PhD (Biophysics) at Harvard University and PhD (Medical Engineering) from Harvard-MIT Health Sciences and Technology (HST) under the guidance of Profs. Ralph Weissleder and Robert S. Langer. After a postdoctoral fellowship with Prof. Hakho Lee at Massachusetts General Hospital, Harvard Medical School, Dr Shao returned to Singapore and started her research group. Her research focuses on developing integrated nanotechnology-based platforms for molecular analyses of novel biomarkers. Her work has been published in top journals such as Nature Biotechnology, Nature Nanotechnology, Nature Medicine, Nature Biomedical Engineering, Nature Communications and highlighted in major reviews and popular news media.
For more information about Shao’s research, visit https://www.huilinshao.com/
Register the webinar here: https://nus-sg.zoom.us/webinar/register/WN_WM0opxx6TSK0NWvTIweQNg
Download the poster here [pdf]