Careers

The SurgiCAL ProtEomics Laboratory (SCALPEL) is seeking an enthusiastic and highly motivated Laboratory Executive to support our molecular and cellular work in the Department of Surgery, Yong Loo Lin School of Medicine (http://medicine.nus.edu.sg/medsur/) on using patient-derived models to develop precision medicine for pancreatic ductal adenocarcinoma (PDAC). We will provide initial training to use cutting-edge techniques in the laboratory and support career growth and development opportunities (i.e., pursuing higher education).

Key Responsibilities

1. To coordinate, collect, process, record, and store clinical specimens (e.g., plasma, biopsies).
2. To support current and future research projects in the laboratory including:
   • Expansion and maintenance of 2D and 3D patient-derived organoid cultures.
   • Molecular/cellular biology-related techniques: Cell viability assay, drug screening, western blotting, quantitative plate-based detection assays, microscopy, genomic DNA/RNA isolation, cDNA synthesis, gel-electrophoresis, and q-PCR/PCR.
3. To record experimental procedures systematically and accurately, present experimental results in a logical manner.
4. To provide frequent updates and plan further experiments under guidance.
5. To assist PI with updating and tracking of grants and other funding applications.
6. To liaise with core facilities, committees, and the administrative office in research-related matters.
7. To maintain and keep track of the procurement, delivery and payment of equipment, consumables, and reagents inventory required by the laboratory.
8. To organise, stock up consumables and maintain the general cleanliness in the laboratory.
9. To set up, maintain core laboratory equipment and provide training for new users.
10. To assume as a safety lead and ensure compliance of the laboratory safety requirements set by regulatory bodies, such as the NUS Office of Safety, Health and Environment (OSHE). Adapt to changes in these regulations and standards as they are announced.
11. To develop, maintain and review standard operating procedures and risk assessment for laboratory activities and processes.

Requirements

• Applicants should possess a BSc (Hons) or MSc in life sciences, biomedical sciences, biochemistry, bioengineering or equivalent from a well-recognised university. 
• Proficient in computer software, including Microsoft Word, Excel and PowerPoint. 
• Previous research experience in molecular/cellular biology, liquid chromatography techniques is a plus. 
• Self-driven, independent, team player, meticulous and have a keen eye for details. 
• Willingness to learn new technologies and techniques (i.e. proteomics-based workflow), tackle both new and routine duties.
• Good organisation and management skills.
• Able to work well in an interdisciplinary and collaborative environment.
• Flexible to adapt to changing environments and project priorities/timelines.
• Able to work at flexible hours occasionally when performing time-sensitive experiments.
• Excellent written and verbal communication skills
• A strong passion for science.

Institute for Health Innovation & Technology (iHealthtech), National University of Singapore
iHealthtech’s vision on “Advancing Health through Innovation” aims to address clinical challenges and needs by developing innovative health technologies and solutions in disease detection, diagnosis, monitoring, and treatment. The institute also focuses on translating health technology, incubating startups, and nurturing young scientists, engineers, and entrepreneurs to impact patients and society.

/202110