NUS researchers pioneer DNA-tagged gold nanoparticles for targeted cancer treatment
- January 24, 2025
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One of the most challenging tasks in cancer therapy is delivering drugs or treatments specifically to targeted tumor cells with high uptake efficiency. Gold nanoparticles, which are much smaller than the width of a human hair, have been utilized in photothermal therapy to destroy cancer cells using heat.
In this study, iHealthtech PI Dr Andy Tay and his team explored how gold nanoparticles of varying sizes and shapes are taken up by cancer cells. Ingeniously, the team tagged the gold nanoparticles with DNA barcodes to investigate whether the size and shape of the particles influence their uptake.
Their study was published in the peer-reviewed scientific journal Advanced Functional Materials.
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