NUS researchers invent powerful tool to gather data on immune response at single-cell level
- June 06, 2023
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Time-resolved assessment of single-cell protein secretion with sequencing (TRAPS-seq) is an innovative technique developed by Assistant Professor Lih Feng Cheow and his research team, which includes Dr Wu Tongjin and Dr Howard John Womersley. This groundbreaking invention enables tracking the precise source cell responsible for protein secretion while also measuring changes in secretion over time. By employing the technique, researchers can gain a deeper understanding of immune cell behaviour, unravelling how these cells respond to different stimuli, thus providing valuable insights into the immune cell’s response kinetics and identifying the critical time points during immune responses.
The research conducted by Assistant Professor Cheow and his team signifies a major advancement in immunology and single-cell analysis. Their innovative TRAPS-seq technique provides a powerful tool for studying immune cell behaviour, unlocking new avenues for developing effective therapeutic strategies for a wide range of diseases.
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